Radioimmunoassay of osteocalcin with polyclonal and monoclonal antibodies.
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چکیده
منابع مشابه
Polyclonal and monoclonal antibodies.
The breadth of repertoire yet beautiful specificity of the antibody response is the key to its physiological efficacy in vivo; it also underpins the attractiveness of antibodies as laboratory and clinical reagents. One aspect of the body's reaction to invasion by a microorganism is the activation and clonal expansion of antigen-reactive B lymphocytes. Once these have matured into plasma cells, ...
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Background: The unique expression of fibromodulin (FMOD) in patients with chronic lymphocytic leukemia (CLL) has been previously reported. Detecting FMOD in CLL patients using specific anti-FMOD mAbs might provide a promising method in detection, monitoring, and prognosis of CLL. Objectives: In this study, we aimed for producing specific antibodies agains...
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It is called an immunoglobulin that is used for neutralization of the foreign pathogens like viruses, bacteria or any foreign bodies invade the blood. When antibodies produced from immunized animals against certain antigen will produce what is called polyclonal antibodies (PAbs) which are mixture of different antibodies produced by many different B cell clones that identify different epitopes (...
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A new method that allows rapid phenotyping of genetic Lp(a) glycoprotein types in large numbers of samples is described. The method is based on sodium dodecyl sulfate gel electrophoresis of reduced serum or plasma in horizontal slab gels followed by immunoblotting with polyclonal anti-Lp(a) lipoprotein or monoclonal anti-Lp(a) glycoprotein antibodies. Phenotyping of 194 unrelated, healthy subje...
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We describe a double-antibody radioimmunoassay for apolipoprotein B with use of monoclonal antibodies. Values for 32 patients with various lipid disorders, obtained with use of one of the monoclonal antibodies (464B1B6), were similar to those obtained with use of a polyclonal antiserum. When we used another monoclonal antibody (465C3D1) the values were significantly lower. Monoclonal antibody 4...
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ژورنال
عنوان ژورنال: Clinical Chemistry
سال: 1989
ISSN: 0009-9147,1530-8561
DOI: 10.1093/clinchem/35.7.1408